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Precious COVID-19 vaccines destined for the Bay Area are having trouble reaching their destinations thanks to a massive winter storm that has battered Southern and Midwestern states, and devastated Texas.

State officials have informed San Mateo County that its weekly shipment of Moderna vaccines would be delayed, according to county spokesman Preston Merchant. The county had been expecting 14,200 doses. Health officials have received no word on when that shipment might arrive.

As a result, some appointments for second shots on Friday may have to be canceled.

“Plans for vaccination clinics for next week are being adjusted as needed, based on when the Moderna doses arrive,” Merchant wrote in an emailed statement. “Vaccine distribution to local health care partners and some large vaccine distribution events will be on hold until we receive updates from the California Department of Public Health about the delivery of vaccine.”

A clinic planned for Friday at San Francisco International Airport will go forward as scheduled, but the clinic likely will administer Pfizer vaccines instead of Moderna.

“A number” of Moderna doses earmarked for Santa Clara County have been delayed due to the weather, according to county spokesman Roger Ross. The county has been able to maintain existing vaccine appointments using the doses it already had on hand.

“The delays have not had a significant effect on vaccination distribution thus far,” Ross wrote in an emailed statement. “Continued delays could result in canceled appointments.

This is a developing story. Check back for updates.